Active Antibiotics Production by Actinomycetes Indigenous To Saudi Arabia Soils

Streptomyces are the most popular among Actinomycetes groups and found in soils worldwide. They form an important part of soil ecology within Actinomycetales order. diverse as secondary antibiotic metabolites such Novobiocin, Amphotericin, Vancomycin, Neomycin, Gentamicin, Chloramphenicol, Tetracycline, Erythromycin Nystatin. Thus, current study was aimed to isolate, identify assess active produced by different actinomyces sp. Saudi Arabian soils. Six samples were collected from desert Al Thumamah area analyzed using GS-MS. Scanning Electron Microscopy used bacterial strains along with their effectiveness (antibiotics) against Gram-positive (Bacillus subtilis, Staphylococcus aureus), negative pathogens (Pseudomonas aeruginosa, Escherichia coli, Salmonella suis, Shigella sonnei) well fungal strain Candida albicans investigated. Thirty (F1-30) isolated F3, F7, F22, F30 have white, gray, pink, yellow red colours respectively. Only ten (F13, F14, F15, F16, FI7, F18, F19, F20, F21, F22) antimicrobial activity at least one pathogen. The optimum growth environment pH 4-10, temperature (300C), NaCl (7% w/v) concentration. According our findings, extreme Arabia is rich its actinobacterial population colouring various physiological biochemical properties. This shows it’s capability generating metabolite elements that could inhibit pathogenic microorganisms.